stroke
Conditions
Interventions
Dual-Target Stimulation Group:high frequency rPMS on Brachial Plexus and high frequency rTMS on iM1
Central Stimulation Group:high frequency rTMS on iM1
Sham Stimulation Group:sham rTMS on iM1
Sponsors
Huashan Hospital, Fudan University, Shanghai, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) First-time stroke, diagnosed by cranial CT or MRI; (2) The onset of the condition occurred between two weeks and 6 months; (3) The presence of motor function impairment (FMA of upper limb <66 points or FMA of lower limb <34 points); (4) The patient does not have significant cognitive impairment.
Exclusion criteria
Exclusion criteria: (1) Previous history of stroke, brain trauma, or brain tumor; (2) Co-occurring severe heart, lung, liver, kidney dysfunction, or other serious somatic diseases; (3) Past history of epilepsy and family history of epilepsy; (4) Implanted metals in the body such as heart pacemakers, metals in the skull, etc. (5) The occurrence of new infarcts or secondary bleeding, and those with deteriorating conditions; (6) Those with severe cervical spine disease, including severe cervical spinal stenosis, and cervical spine instability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment upper limb, FMA-UE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Action Research Arm Test, ARAT;modified Barthel index, MBI;motor evoked potential, MEP;Wolf motor function test, WMFT;central motor conduction time, CMCT;MAS;functional near-infrared spectroscopy, fNIRS; | — |
Countries
China
Contacts
Public ContactLimin Sun
Huashan Hospital, Fudan University
Outcome results
None listed