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Preclinical evaluation of Tianjing Zelan formula in the treatment of polycystic ovary syndrome

Preclinical evaluation of Tianjing Zelan formula in the treatment of polycystic ovary syndrome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077822
Enrollment
Unknown
Registered
2023-11-21
Start date
2022-06-10
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Experimental Group:Tianjing Zelan traditional Chinese medicine

Sponsors

Jiangsu Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with PCOS based on Western diagnostic criteria; 2. It is in line with the damp-heat type of liver meridian in traditional Chinese medicine 3. Female, aged between 15 and 35 years old; 4. Patient's informed consent. If the above four criteria are met at the same time, they can be included.

Exclusion criteria

Exclusion criteria: 1. Positive pregnancy test; 2. Moderate to severe abnormal liver and kidney function (more than twice the normal value); 3. Hypertension; 4. Abnormal coagulation function; 5. Anemia; 6. Excessive menstruation, disintegrating and prolonged menstruation; 7. Patients with anxiety, depression and other mental disorders; 8. Oral administration of hormones, insulin sensitizers and other endocrine-regulating drugs within 3 months; 9. Combined with reproductive system tumors (excluding uterine fibroids =3cm); 10. Complicated with serious cardiovascular, cerebrovascular, digestive, respiratory, hematopoietic and other diseases.

Design outcomes

Primary

MeasureTime frame
Menstrual cycle;Testosterone;Insulin Resistance Index;Free testosterone;

Secondary

MeasureTime frame
Luteinizing Hormone/Follicular Stimulating Hormone;Anti-mullerian hormone;TCM Syndrome scoring form;Ferriman-gallwey hirsutism rating scale;Acne Pillsbury Rating Scale;Fasting blood glucose;Fasting insulin;Fasting Blood Lipids;Sex hormone binding globulin;Dehydroepiandrosterone;BMI;

Countries

China

Contacts

Public ContactRen Qingling

Jiangsu Provincial Hospital of Traditional Chinese Medicine

yfy0047@njucm.edu.cn+86 134 5193 9139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026