Prostate cancer
Conditions
Interventions
Healthy volunteers or prostate cancer patients:CD13 PET/CT examination
Sponsors
Department of Urology, Xiangya Hospital, Central South University
Eligibility
Sex/Gender
Male
Age
18 Years to 78 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-78 years, male; 2.Healthy volunteers or clinical suspicion or pathological confirmation of prostate cancer; 3.No history of other autoimmune diseases, acute infections, acute traumas; 4.Treatment-naïve or minimally treated patients (prior to specific therapies like ADT or novel hormonal therapies); 5.Basic normal cardiac, pulmonary, hepatic, and renal function; 6.Able to cooperate in observing adverse events and treatment efficacy; 7.Written informed consent from patients or their legal representatives; 8.Normal coagulation function.
Exclusion criteria
Exclusion criteria: 1.HIV antibody positive or having other acquired or congenital immunodeficiency diseases or organ transplant history; 2.Fever with a body temperature above 38°C or an active infection that could significantly affect the clinical trial; 3.Uncontrolled hypertension (systolic blood pressure over 160 mmHg or diastolic blood pressure over 100 mmHg); 4.Significant cardiovascular abnormalities (e.g., myocardial infarction, superior vena cava syndrome, severe heart disease of grade 2 or higher before enrollment, or as determined by the investigator, patients at risk of increased ventricular arrhythmia); 5.History of cardiac arrhythmia (multifocal ventricular premature contractions, bigeminy, trigeminy, ventricular congenital long QT syndrome); 6.Tachycardia or uncontrolled atrial fibrillation with symptoms or requiring treatment (CTCAE Grade 3), or asymptomatic sustained tachycardia; 7.Left bundle branch block; 8.Third-degree atrioventricular block or symptomatic sick sinus syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;SUVmean; | — |
Countries
China
Contacts
Public ContactYi Cai
Department of Urology, Xiangya Hospital, Central South University
Outcome results
None listed