menopausal syndrome
Conditions
Interventions
Control group:Bujiale 1mg + Dydrogesterone 5mg/day, continuous administration for 90 days
Experimental group 1:Tiepi Fengdou Granules (3g/pack), 2 packs/time, 3 times a day, for 90 days
Experimental group 2:Tiepi Fengdou Granules (3g/pack), 2 packs/time, 3 times a day, combined with Bujiale 1mg + Dydrogesterone 5mg/day, taken continuously for 90 days
Sponsors
Women's Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Female aged 40-65 years old; 2. Menopause for more than 12 months and pregnancy excluded, follicle-stimulating hormone >40U/L and estradiol <10-20pg/ml; 3. Have a uterus and at least one ovary; 4. Accompanied by vasomotor symptoms such as hot flashes or symptoms of autonomic nervous system dysfunction such as palpitations, dizziness, headache, insomnia, tinnitus, or psychiatric and neurological symptoms such as agitation, anxiety, low mood, depression, or vaginal dryness, dyspareunia, Women with recurrent vaginal infections, difficulty urinating, frequent urination, urgency and other urogenital symptoms, or osteoporosis; 5. Voluntarily participate and sign the consent form to enter clinical research.
Exclusion criteria
Exclusion criteria: 1. Those who have undergone artificial menopause due to uterine or bilateral ovary removal or other reasons, such as radiotherapy and chemotherapy; 2. Women who are using other drugs and treatments to relieve menopausal-related symptoms; 3. People with wind-cold-damp paralysis, those with warm-heat disease whose yin is not injured in the early stage, those with damp-warm disease whose dryness has not resolved, or those with spleen and stomach deficiency; 4. People who have experienced discomfort while taking Tiepi Fengdou.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sex hormone test;Liver and kidney function tests;Thyroid function test;Ultrasound of uterus and breast;Vaginal microecology examination; | — |
Countries
China
Contacts
Public ContactJianhong Zhou
Women's Hospital, Zhejiang University School of Medicine
Outcome results
None listed