Breast cancer due to post-traumatic stress disorder
Conditions
Interventions
Treatment group:Anshen Dingzhi Fang+Paroxetine
Sponsors
The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: a. All cases were confirmed as breast cancer by pathology or cytology, the stage criteria are patients below stage II, and all patients have been treated by surgery combined with radiotherapy or chemotherapy; B. PTSD symptoms were evaluated by PCL-C for at least 1 month, and the diagnosis of PTSD was confirmed by CAPS evaluation; C. KPS (Karnofsk) score>60, estimated survival>6 months; D. 18-70 years old, with education level above primary school; E. The patient's condition is stable, without severe center of gravity, liver, brain, kidney and other organic damage or bone marrow hematopoietic dysfunction; F. The patient has clear mind, no dyslexia and can complete the questionnaire; G. The patient can understand and agree to participate in this study and has good compliance.
Exclusion criteria
Exclusion criteria: A. Non primary breast cancer; B. Previous history of primary or secondary mental disorders, taking psychiatric drugs; C. Parents with mental disorders within three generations; D. Special psychotherapy (cognitive behavioral therapy focusing on trauma, eye movement desensitization and reprocessing); E. In addition to breast cancer, it is experiencing other major traumatic events; F. Breast cancer patients with brain metastasis; G. Pregnant women H. Participants in other clinical studies within the past month; I. According to the judgment of the researchers, there are other reasons that may lead to loss of follow-up or may not be suitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-traumatic stress disorder diagnostic scale (CAPS);After trauma Self rating stress disorder scale (PCL-C);PCL-C scale reduction rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life scale for breast cancer patients (FACT-B);Breast PRO scale of traditional Chinese medicine after cancer surgery;Self-Rating Anxiety Scale;Self-Rating Depression Scale;Laboratory related indicators: blood inflammation related indicators, HPA axis related indicators, estrogen related indicators, immune related indicators; | — |
Countries
China
Contacts
Public ContactZhu Yongfu
Department of Oncology, First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Outcome results
None listed