metastatic colorectal cancer
Conditions
Interventions
intervention group:Oral administration twice a day, 5 capsules each time, treatment period: 30 days (taking 20 days and resting for 10 days), treatment period = 3 months is considered positive exposur
Sponsors
Chongqing University Three Gorges Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Age = 18 years old, regardless of gender; ? Pathological staging of metastatic colorectal cancer with no chance of radical surgery; ? KPS score = 60 points; ? Expected survival time = 3 months; ? Without strict center of gravity, abnormal lung, liver, and kidney functions; ? Non grade II and above diarrhea (CTCAE v4.03 grade); ? Having measurable lesions that meet the RECIST 1.1 standard; ? Volunteer to join this study and sign an informed consent form;
Exclusion criteria
Exclusion criteria: ? Merge with other malignant tumors; ? Concomitant severe heart, liver, and kidney diseases and complications; ? There are various factors that affect the absorption of oral drugs, such as difficulty swallowing or intestinal obstruction. Suffering from malabsorption syndrome or other diseases that affect gastrointestinal absorption, or suffering from active peptic ulcer; ? Any unstable situation that may endanger patient safety and research compliance; ? Subjects with poor compliance or inability to cooperate in completing the study were judged by the researcher; ? Other situations that the researchers believe are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| progression-free survival; | — |
Countries
China
Contacts
Public ContactWang Lei
Chongqing University Three Gorges Hospital
Outcome results
None listed