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Prognosis in multiple myeloma by Copy Number Variants identified by Shallow whole-genome sequencing: a multicenter research

Prognosis in multiple myeloma by Copy Number Variants identified by Shallow whole-genome sequencing: a multicenter research

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077768
Enrollment
Unknown
Registered
2023-11-20
Start date
2023-11-20
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Myeloma

Interventions

Case series:no

Sponsors

Xinqiao Hospital Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Diagnosed with multiple myeloma according to IMWG criteria. 2) Karyotype analysis and FISH detection were performed at the time of initial diagnosis 3) ECOG performance score 0-3 4) Expected survival time = 3 months 5) Subject must sign the informed consent

Exclusion criteria

Exclusion criteria: 1) Non-initial diagnosis and treatment; Other plasma cell diseases of inactive multiple myeloma, including primary amyloidosis, MGUS (monoclonal gammaglobulinemia of unknown significance) or smoldering myeloma and solitary plasma cell tumor; 2) Karyotype analysis and FISH were not detected at the initial diagnosis; 3) Combined with other malignant tumors; 4) Active tuberculosis patients and HIV-positive patients; 5) Drug addiction or mental illness; 6) Treatment related to myeloma cannot be performed due to various reasons such as physical condition; 7) Refuse to join the study patient; 8) The sample quality is unqualified; 9) Unable to follow the research protocol

Design outcomes

Primary

MeasureTime frame
Technical indicators(Positive rate,Sensitivity, specificity);

Secondary

MeasureTime frame
Prognostic stratification index;overall survival;progression free survival;

Countries

China

Contacts

Public ContactGao Li/Zhang Xi

Xinqiao Hospital Army Medical University

gaotiantiantiger@163.com+86 23 6876 3198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 29, 2026