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Study on the effect of ciprofol on pharyngeal reflex and pharmacology in gastroscope diagnosis and treatment

Study on the effect of ciprofol on pharyngeal reflex and Pharmacodynamics in gastroscope diagnosis and treatment

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077741
Enrollment
Unknown
Registered
2023-11-17
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal disease

Interventions

Cipropofol group:Cipropofol induction

Sponsors

Guangxi Hospital Division of The First Affiliated Hospital,Sun yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ? Age 18-70 years old; (2) Body mass index between 18 and 30 kg/m2 (3) american society of anesthesiologists (ASA) grade I to II; ?Mallampati was classified into ?~? grades; (5) Various auxiliary examinations have been improved before surgery, and there is no obvious contraindication of elective surgery anesthesia.

Exclusion criteria

Exclusion criteria: ? Severe hypertension or diabetes or chronic obstructive pulmonary disease; 2 Used sedative drugs, antiemetic drugs, antipruritic drugs 24 h before surgery, or used monoamine oxidase inhibitors or antidepressants within 15 days before surgery; ? People with chronic pain who use analgesics, psychotropic drugs and alcohol for a long time; History of liver surgery, renal or liver insufficiency, history of gastrointestinal ulcers or bleeding tendency; ? History of opioid allergy; ? Complicated with tumor, serious cardiovascular and cerebrovascular diseases; Diseases associated with abnormal airway management of the upper respiratory tract, respiratory insufficiency, or sleep apnea that may cause dyspnea.

Design outcomes

Primary

MeasureTime frame
Blood pressure;Heart rate;Apnea or not;ASA score;Duration of gastroscope insertion;Time to fully alertness;MOAA/S scores;

Secondary

MeasureTime frame
BMI;Satisfaction ratings;resuce sedation;irritability or not;

Countries

China

Contacts

Public ContactHuang Kecheng

Guangxi Hospital Division of The First Affiliated Hospital,Sun yat-sen University

119737479@qq.com+86 173 0771 1362

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026