Gestational diabetes mellitus
Conditions
Interventions
Intervention group:Establish an anti-inflammatory diet intervention group composed of one nutritionist, one obstetrician-gynecologist, one health education nurse, and one research personnel. Through g
? Increase the intake of dark-colored vegetables
? Choose whole grains
? Increase the proportion of white meat
? Reduce fat intake
? Use plant-based oils
? Avoid pickled and salty foods. To facilitate daily guidance on an anti-inflammatory diet, the research team has developed the "AnXinYouYun" WeChat mini-program in the early stage. This mini-program
Control group:Routine diet and health education for GDM pregnant women.
Sponsors
Anhui Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Singleton pregnancy; 2. Aged between 20 to 40 years old; 3.Residing in the urban area of Hefei during pregnancy; 4. Able to clearly answer questionnaire questions.
Exclusion criteria
Exclusion criteria: 1. Having mental disorders such as depression; 2.Conceived through assisted reproductive techniques; 3. Having pre-existing conditions like diabetes, hypertension, or systemic lupus erythematosus before pregnancy; 4. Exhibiting serious liver or kidney diseases during follow-up; 5. Being in an acute inflammatory phase during follow-up; 6. Having used antibiotics during follow-up; 7. For the GDM exposure group, exclude those who took hypoglycemic drugs during the follow-up; For the healthy control group, exclude those with pregnancy complications (including gestational diabetes, hypertension, cholestasis, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood-glucose;Biomarkers for chronic inflammation;Vascular endothelial function;Detection of intestinal microbes in the feces of pregnant women in the second and third trimester of pregnancy; | — |
Countries
China
Contacts
Public ContactZhu Peng
Anhui Medical University
Outcome results
None listed