Cough variant asthma, CVA
Conditions
Interventions
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: ? The age ranges from 3 to 14 years old, regardless of sex. ?The diagnosis of cough variant asthma is evaluated by pediatric specialists, according to the guidelines for the diagnosis, Prevention and treatment of bronchial Asthma in Children 2016: a. Cough lasted for more than 4 weeks, often occurred or aggravated during exercise, night and / or early morning, mainly dry cough, not accompanied by wheezing. b. Clinically, there were no signs of infection or ineffective treatment with antibiotics for a long time. c. Diagnostic treatment of anti-asthma drugs is effective; chronic cough caused by other causes is excluded; d. Positive bronchial provocation test and / or diurnal variation rate of PEF (continuous monitoring for 2 weeks) = 13%. e.Personal or first-or second-degree relatives history of allergic disease, or allergen test positive. ? the diagnosis of typical asthma is made by specialists in combination with the 2016 Edition of guidelines for the diagnosis, Prevention and treatment of bronchial Asthma in Children.
Exclusion criteria
Exclusion criteria: ?Hepatitis B, tuberculosis and other chronic infections, malnutrition, craniofacial deformities, thoracic deformities, and genetic syndromes; ? Suffering from other chronic lung diseases, such as bronchiectasis, cystic fibrosis, pulmonary interstitial disease, etc.; ? Wheezing caused by other reasons (such as bronchopulmonary dysplasia, primary ciliary dyskinesia, congenital airway malformations, mechanical obstruction, heart disease, neuromuscular abnormalities, etc.) or combined with primary immunodeficiency diseases; ? Complicated with heart, liver, kidney, hematopoietic system and other diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mel-scale Frequency Cepstral Coefficients of respiratory sounds in children with cough variant asthma; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough consultation and clinical symptoms; | — |
Countries
China
Contacts
Public ContactQi Zhang
China-Japan Friendship Hospital
Outcome results
None listed