Comparison of electroencephalographic characteristics of patients with different ages at loss of consciousness induced by general anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300077716

Enrollment

Unknown

Registered

2023-11-16

Start date

2023-12-20

Completion date

Unknown

Last updated

2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Loss of Consciousness

Interventions

Young group:NA

Elderly group:NA

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: ? Young group (aged 18~40 years), Elderly group (aged = 65 years) ? ASA I–II, patients undergoing elective surgery under general anesthesia ? There are no significant abnormalities in the functions of the heart, liver, lungs and kidneys ? Not taking opioids or sedative hypnotic drugs for a long time ? No history of mental and nervous system disease ? No hearing impairment ? Right-handed

Exclusion criteria

Exclusion criteria: ? Abuse of drugs or alcohol ? Severe Obesity (BMI > 30kg m-2) ? Preoperative MMSE score < 24 ? Preoperative administration of sedative drugs ? Allergy to propofol

Design outcomes

Primary

Measure	Time frame
Plasma target concentration of propofol during consciousness loss;Propofol dosage during consciousness loss;Time required for consciousness to disappear;	—

Secondary

Measure	Time frame
Power spectral density;Functional connectivity;Graph theory indicators;	—

Countries

China

Contacts

Public ContactGu Weidong

Huadong Hospital affiliated to Fudan University

mcwgwd@163.com+86 189 1816 9021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026