gout
Conditions
Interventions
Integrated traditional Chinese and western medicine group:Huazhuo Sanjie Zhubi granules + allopurinol tablets
Western medicine section:Allopurinol tablets + Huazhuo Sanjie Zhubi Granule mimics
Chinese medicine section:Huazhuo Sanjie Zhubi granules + allopurinol tablets mimics
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) patients who met the gout classification criteria and the diagnosis of chronic gout arthritis; 2) in accordance with the diagnosis of spleen deficiency, damp heat and phlegm turbidity and blood stasis; 3) Male and female aged from 18 to 65 years old; 4) no medications that could interfere with study observations during the 15 days before enrollment; 5) Patients informed and consented to participate in this study.
Exclusion criteria
Exclusion criteria: 1) patients with severe joint deformity and multiple tophi with local ulceration; 2) severe organ lesions or mental disorders; 3) allergy to or contraindication to the drugs involved in the study protocol; 4) pregnant or breastfeeding patients; 5) those who were deemed by the investigator to be ineligible for enrollment in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood uric acid control rate;Recurrent frequency and duration of acute gouty arthritis;Reduction rate of urate crystal deposition on energy spectrum CT;Traditional Chinese Medicine Syndrome Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The degree of pain in the recurrence of acute gouty arthritis;Average dosage of allopurinol;Fluctuation of blood uric acid;Tongue coating score;ESR;CRP; | — |
Countries
China
Contacts
Public ContactWANG Hailong
Dongzhimen Hospital, Beijing University of Chinese Medicine
Outcome results
None listed