superficial corneal defects
Conditions
Interventions
Test group:Biological amniotic membrane for ophthalmology produced by Tido Biotechnology (Nanjing) Co., Ltd
Control group:Wet biological amniotic membrane produced by Jiangxi Ruiji Biotechnology Co., Ltd
Sponsors
Wenzhou Medical University Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Superficial cornea defects caused by various reasons; 2. Age range from 18 to 65 years old, regardless of gender; 3. Voluntarily participate in this experiment and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. The depth of corneal defect is greater than 1/3 of corneal thickness; 2. Chemical or thermal burns with limbal ischemia exceeding 1/4; 3. Eye infection in active phase; 4. Combined eyelid abnormalities and glaucoma; 5. Severe allergic constitution or allergic to test materials and medication; 6. Pregnant, planned or lactating women; 7. Participated in other clinical trials within the past 3 months; 8. Other situations that the researcher deems unsuitable for participation in this experiment. Those who meet any of the above criteria cannot be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective rate of repairing superficial cornea defects,%; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal defect area;Ocular symptom score;Amniotic membrane in-position rate;Conjunctival congestion rating; Best corrected visual acuity; | — |
Countries
China
Contacts
Public ContactWei Chen
Eye System Of Wenzhou Medical University
Outcome results
None listed