Lung Cancer Related Anemia and Serum Iron Deficiency
Conditions
Interventions
control group:Ferrous succinate
Treatment group:Ferrous succinate and Shuanghuang Yangxue Decoction
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients with lung cancer diagnosed by pathology or cytology and meeting the diagnostic criteria for mild to moderate anemia: refer to the World Health Organization's anemia grading standard in the Clinical Practice Guide for Tumor related Anemia (2022 Edition) of the Chinese Society of Clinical Oncology (CSCO): Grade 0 (normal value): Hb of adult males is not less than 130g/L, Hb of non pregnant adult females is not less than 120g/L, and Hb of pregnant adult females is not less than 110g/L; Level 1 (mild): 110g/L~normal value; Grade 2 (moderate): 80g/L~109g/L; Grade 3 (severe):<80g/L; (2) Meet the standard of low serum iron level: according to the Standard for Diagnosis and Efficacy of Hematologic Diseases, serum iron<8.95 µ Mol/L is the standard of low serum iron level; (3) Those who have not received radiotherapy and chemotherapy in the past or have completed radiotherapy and chemotherapy for more than 1 month; (4) The TCM syndrome classification conforms to the patients with deficiency of both Qi and blood; (5) Patients who have not been treated with iron, EPO, blood transfusion, Qi tonifying and blood nourishing prescription or Chinese patent medicine 1 month before admission; (6) Cassegrain score = 60; (7) Age = 18 years old and = 80 years old, regardless of gender; (8) Those who voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Acute blood loss or hemolysis; (2) Those who have participated in or are participating in other drug related clinical trials in the past month; (3) Those who are allergic to the study drug during treatment; (4) People with severe heart, liver, kidney and other organ dysfunction; (5) Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective rate of anemia correction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine examination;Indicators of anemia;Immunity index;Inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactJun Shi
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed