Influence of external chest-wall compression on respiratory mechanics in patients with low compliance ARDS

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300077693

Enrollment

Unknown

Registered

2023-11-16

Start date

2023-12-01

Completion date

Unknown

Last updated

2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS

Interventions

Test group: external chest-wall compression

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. 41 consecutive patients admitted to the Department of Critical Care Medicine of Baoding First Central Hospital due to ARDS were enrolled. The definition of ARDS follows the Berlin definition (8); 2. Mechanical ventilation (PB840, US), volume control mode, and deep sedation (with or without muscle relaxation therapy) to ensure that the patient does not have spontaneous breathing; 3. Over 18 years old ; 4.CRS (respiratory system compliance)=35 ml/cmH2O

Exclusion criteria

Exclusion criteria: The exclusion criteria were: severe hemodynamic instability (blood pressure could not be maintained in patients with NE>0.5ug/kg/min), pregnancy, and factors that could not be used for chest wall loading (such as rib fractures, severe chest burns, severe chest deformities, etc.).

Design outcomes

Primary

Measure	Time frame
respiratory system compliance;	—

Secondary

Measure	Time frame
plateau pressure;driving pressure ;oxygenation index;heart rate;mean arterial pressure;color doppler ultrasond indicator ;	—

Countries

China

Contacts

Public ContactYan Wenwen

Baoding NO.1central hospital

yan1wen2wen3456@163.com+86 134 7222 6912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026