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Comparative study on the effects of Kangfuxin liquid combined with G-CSF cryotherapy and ice saline cryotherapy on oral mucositis and upper gastrointestinal injury in hematopoietic stem cell transplantation patients

Comparative study on the effects of Kangfuxin liquid combined with G-CSF cryotherapy and ice saline cryotherapy on oral mucositis and upper gastrointestinal injury in hematopoietic stem cell transplantation patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077686
Enrollment
Unknown
Registered
2023-11-16
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucositis

Interventions

kangfuxin group:NA
control group:NA

Sponsors

The Second Affiliated Hospital of the Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Meets the indications for hematopoietic stem cell transplantation 2) Preconditioning of drugs that are prone to oral mucositis and upper gastrointestinal damage, including but not limited to the use of drugs such as melphalan, mefaram, cetopide, and methotrexate. 3) Patients receiving hematopoietic stem cell transplantation; 4) The patient's family member signs an informed consent form for hematopoietic stem cell transplantation.

Exclusion criteria

Exclusion criteria: 1) Merge severe underlying diseases; 2) Severe active infection before transplantation; 3) Have a history of oral mucositis; 4) Suffering from mental illness; 5) According to the judgment of the researchers, the patient has other unsuitable enrollment situations.

Design outcomes

Primary

MeasureTime frame
Incidence of mucosal inflammation;

Secondary

MeasureTime frame
Recovery time for mucositis;Degree and duration of NRS pain;Observation of discomfort in the upper gastrointestinal tract;

Countries

China

Contacts

Public ContactFeng Yimei

The Second Affiliated Hospital of the Army Medical University

yimeifeng@163.com+86 134 5299 3609

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026