Infertility
Conditions
Interventions
Observation group:NA
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
Female
Age
No minimum to 38 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 1.1 ng/mL, basal antral follicle count (AFC) > 5; 5. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of drug allergy related to ovulation induction; 2. Gynecological related diseases: genital tract malformations (such as unicornuate uterus/immature uterus/double cervix, etc.), stage III ~ IV endometriosis, abnormal uterine bleeding, untreated hydrosalpinx and intrauterine adhesions, etc.; 3. Adenomyosis; 4. Severe untreated endocrine and metabolic diseases (such as hyperprolactinemia/hyperandrogenism/hypothyroidism, etc.), severe cardio-cerebral related diseases (such as hypertension/cerebral infarction/congenital heart disease, etc.), sexually transmitted diseases (such as syphilis/AIDS, etc.); 5. Endometrial thickness < 8 mm on the trigger day; 6. Patients scheduled for whole embryo freezing; 7. Recurrent miscarriage (with two or more consecutive spontaneous abortions with the same partner), repeated implantation failure (RIF) patients (repeated implantation failure criteria: women under 40 years of age, at least four high-quality embryos or two high-quality blastocysts were transplanted in at least three fresh or frozen cycles to achieve clinical pregnancy; High-quality cleavage stage embryos: 7-9 cells grade 1-2 embryos; high-quality blastocysts: 4BB and above blastocysts); 8. At least one of the couples received genetic diagnosis (PGD) and preimplantation genetic screening (PGS) before sperm donation or egg donation or embryo transfer; 9. Patients with positive serum pregnancy test; 10. Patients with contraindications to double embryo transfer (such as history of cesarean section, uterine malformations, previous pregnancy-induced hypertension or pregnancy-induced diabetes and other pregnancy complications); 11. Other conditions that the researchers considered inappropriate for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| premature LH peak rate;Embryo implantation rate; | — |
Countries
China
Contacts
Public ContactCuilian Zhang
Henan Provincial People's Hospital
Outcome results
None listed