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Effects of cyclopofol on hemodynamics during induction of general anesthesia and postoperative recovery quality in elderly patients undergoing gastrointestinal surgery

Effects of cyclopofol on hemodynamics during induction of general anesthesia and postoperative recovery quality in elderly patients undergoing gastrointestinal surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077643
Enrollment
Unknown
Registered
2023-11-15
Start date
2023-02-13
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal tumors

Interventions

P group:Propofol1.5-2.5mg/kg induction and 4-12 mg/kg/h maintenance
C group:Ciprofol 0.3-0.5mg/kg induction and 0.8-2.4mg/kg/h maintenance

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 65 =years old; ASA grade I~III; Patients planning gastrointestinal surgery.

Exclusion criteria

Exclusion criteria: Severe organ dysfunction; Poor blood pressure control (severe hypertension or hypotension); Preoperative cognitive impairment or history of mental illness, unable to cooperate; Individuals with a history of allergies to the medication used.

Design outcomes

Primary

MeasureTime frame
Incidence of hypotension;

Secondary

MeasureTime frame
Heart rate (HR);Mean arterial pressure (MAP);Injection pain;MMSE rating;QoR-15 rating;Postoperative complications;Extubation time;Adverse cardiovascular events;Length of hospital stay;Use of vasoactive drugs;Bispectral index;Vital signs at different time points ;

Countries

China

Contacts

Public ContactZhongyu Wang

The First Affiliated Hospital of Zhengzhou University

sunsy1122@163.com+86 185 3861 8579

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026