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Comparison of the effects of remazolam and propofol on rapid postoperative recovery in elderly debilitating patients based on perioperative frontal EEG features.

Comparison of the effects of remazolam and propofol on rapid postoperative recovery in elderly debilitating patients based on perioperative frontal EEG features.

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077641
Enrollment
Unknown
Registered
2023-11-15
Start date
2023-11-02
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Debilitating elderly patients

Interventions

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1)Aged 60 to 85 years old; (2)Patients underwent prostatectomy in our hospital; (3)Patients considered debilitating using the Frail Scale scale

Exclusion criteria

Exclusion criteria: (1) People allergic to emulsions, remimazolam and opioids; (2) Cranial CT examination was performed to exclude organic brain injury,patients diagnosed with epilepsy, anxiety and depression or severe physical diseases,and who had previous encephalopathy; (3) Patients with drug dependence, substance abuse, or who use anticonvulsants, sedatives, and depressants in the last three months; (4)Patients with audio-visual disorders, long-term insomnia, and being unable to communicate for other reasons; (5) Patients predicted by the anesthesiologist to have or to have a difficult airway.

Design outcomes

Primary

MeasureTime frame
Recovery Quality Score;

Secondary

MeasureTime frame
Patient baseline data;Hemodynamic data during the surgery;Dose of anesthetic used during operation;Dose of vasoactive agent used during operation;Intraoperative adverse effects;Intraoperative EEG features;The occurrence of postoperative POD;Operation and anesthesia time, wake up time;Postoperative complications of each organ system;All-cause mortality at 1 year after surgery;

Countries

China

Contacts

Public ContactGuanghong Xu

The First Affiliated Hospital of Anhui Medical University

xuguanghong2004@163.com+86 138 5694 9535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026