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Effect of ultrasound-guided modified intercostal nerve block after radical mastectomy:a randomised controlled trial

Effect of ultrasound-guided modified intercostal nerve block after radical mastectomy:a randomised controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077640
Enrollment
Unknown
Registered
2023-11-15
Start date
2023-11-10
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Interventions

control group:Intercostal block with saline
Experimental group:Intercostal Block with 0.33% Ropivacaine

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients underwent modified radical mastectomy in our hospital during November 2023 to March 2024.2.aged 18 to 65 years old 3.ASA I-III 4. BMI15-35kg/m2

Exclusion criteria

Exclusion criteria: 1.Contraindications to nerve block include, but are not limited to, allergies to anesthetics 2.Opioid use for more than 4 weeks or preoperative chronic pain for more than 3 months. 3.Severe comorbidities, including but not limited to renal insufficiency,hepatic insufficiency,and heart failure, or ASA = IV; 4.BMI>35kg/m2or <15 kg/m2; 5.The patients were not able to take part in the evaluation of postoperative analgesia. 6.Ultrasound scans are anatomically difficult and can not be used for nerve block surgery. 7.No informed consent was signed.

Design outcomes

Primary

MeasureTime frame
VAS scores were obtained at rest and movement;

Secondary

MeasureTime frame
Dose of anesthetic used during operation;Operation and anesthesia time, wake up time;Postoperative use of salvage drugs in patients;Postoperative adverse events;Recovery Quality Score;Postoperative sleep status of the patients;Incidence of nausea and vomiting within 24 hours after surgery;Incidence of postoperative delirium;First time out of bed after surgery;VAS scores were obtained at rest and movement;Hemodynamics;Hospital stay/Postoperative hospital stay;Total hospitalization costs/Costs of anesthesia;

Countries

China

Contacts

Public ContactGuanghong Xu

The First Affiliated Hospital of Anhui Medical University

xuguanghong2004@163.com+86 138 5694 9535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026