Adolescent Scoliosis
Conditions
Interventions
Depression group:None
Non-depressive group :None
Sponsors
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Age = 10 years and Age <18 years 2.Proposed elective scoliosis orthopedic surgery 3.ASA classification (American Association of Anesthesiologists) is grade I-III 4.Agreed to participate in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Refuse to participate in this study; 2. There is acute and chronic pain before surgery. 3 History of the use of long-term oral analgesics and opioid analgesics before surgery; 4 Severe liver dysfunction (Child-Pugh C), renal dysfunction (preoperative dialysis) or expected survival =24 hours of patients; 5 Preoperative schizophrenia, bipolar disorder, epilepsy, myasthenia gravis; 6 Unable to communicate before surgery due to coma, severe dementia, speech impairment or severe hearing impairment; 7 Preoperative severe hypertension, sinus tachycardia, acute coronary syndrome within 1 week, severe heavy intracranial hypertension; 8 Refuse to use the postoperative self-controlled analgesic pump; 9 Use of ketamine/ E-sketamine during surgery 10. Those who is participating in other interventional clinical studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Moderate and severe pain (NRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression score (CDI);Pain score (NRS);Orthopedic condition score (SRS-22);Quality of life score (SF-36);Sleep score (NRS);Cognitive function score;The type, frequency and dosage of analgesic drugs;Occurrence of delirium;30days after surgery(survival or death);Complication;postoperative hospitalization; | — |
Countries
China
Contacts
Public ContactBo Jinhua
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School2023-
Outcome results
None listed