Perinatal infection
Conditions
Interventions
Experimental group (oral azithromycin group):Azithromycin 2g was administered at the time of labor (at least 2cm dilation of the uterine opening)
Control group (blank group):No oral medication during labor
Sponsors
Drum Tower Hospital Affiliated to Nanjing University Medical School
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years old; 2. The gestation age is 37 weeks or more; 3. Singleton gestation; 4. No fever or other known infectious diseases; 5. Health care workers assess pregnant women who intend to use one or more methods of induction; 6. The patients who signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergic to azithromycin or other macrolide antibiotics; 2. Use of azithromycin or other macrolide antibiotics within 3 days prior to randomization; 3. Planned cesarean section or full uterine opening before randomization; 4. Fetal death or known major congenital abnormalities; 5. Any disease that is considered contraindicated by a pregnant woman with a serious maternal disease or by an obstetrician (e.g. mental disorder, arrhythmia, structural heart disease, pulmonary edema, severe liver disease, kidney disease, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of intrapartum infection and/or puerperal disease; | — |
Secondary
| Measure | Time frame |
|---|---|
| Delivery mode;Maternal complications;Neonatal complications; | — |
Countries
China
Contacts
Public ContactDai Yimin
Drum Tower Hospital Affiliated to Nanjing University Medical School
Outcome results
None listed