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Clinical research on the efficacy and safety of using Ambroxol Hydrochloride Solution for Inhalation to alleviate childhood wheezing

Clinical research on the efficacy and safety of using Ambroxol Hydrochloride Solution for Inhalation to alleviate childhood wheezing

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077620
Enrollment
Unknown
Registered
2023-11-14
Start date
2022-07-21
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children wheezing

Interventions

Experimental group:On the basis of essential drug treatment, add "Ambroxol Hydrochloride Solution 2ml+ saline 2ml inhalation twice a day".
Placebo group:On the basis of essential drug treatment, add "inhaling saline 4ml twice a day".

Sponsors

Shunde Women and Children's Hospital of Guangdong Medical University (Foshan Shunde District Maternal and Child Health Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Months to 6 Years

Inclusion criteria

Inclusion criteria: Children with wheezing bronchitis or wheezing pneumonia with sticky sputum symptoms 6 Months-6 years old No limitation of gender Inpatient Sign the informed consent form

Exclusion criteria

Exclusion criteria: Participated in other clinical trials within 4 weeks prior to the start of this study Ambroxol preparation is being taken or was used within 3 days before the start of this test; Being taking or having used sodium cromolyn preparation within 2 weeks prior to the start of this experiment; Taking medication with a pH higher than 6.3; Patients with bronchial damage or excessive secretion; Patients with peptic ulcer; Patients with renal insufficiency; Complications with other extrapulmonary inflammatory diseases; Critical patients or those with Bronchospasm; Patients with other serious illnesses.

Design outcomes

Primary

MeasureTime frame
Wheezy phlegm sound;Wheezing ;

Secondary

MeasureTime frame
Lung function;Fractional exhaled nitric oxide;Blood oxygen saturation;

Countries

China

Contacts

Public ContactWang Yajun

Shunde Women and Children’s Hospital Guangdong Medical University

yajun2018@qq.com+86 757 2297 9620

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026