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A Study on Multiple Pathways and the Tumor Microenvironment Leading to Chemotherapy Resistance of Cervical Cancer by Single-Cell RNA Sequencing Reveals

A Study on Multiple Pathways and the Tumor Microenvironment Leading to Chemotherapy Resistance of Cervical Cancer by Single-Cell RNA Sequencing Reveals

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077612
Enrollment
Unknown
Registered
2023-11-14
Start date
2023-11-15
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer

Interventions

HLA-G positive:None
HLA-G negative:None

Sponsors

The Seventh Medical Center of Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Cervical cancer was confirmed by pathology; 2) Complete case data; 3) Received surgical treatment with extensive total hysterectomy ± bilateral adnexectomy + pelvic lymphadenectomy; 4) Patients aged 18-75 years.

Exclusion criteria

Exclusion criteria: 1) Other malignant tumors, endocrine diseases, mental diseases, autoimmune diseases; 2) Complicated with serious heart, kidney, liver and other underlying diseases; 3) Patients with residual cervical cancer after subtotal hysterectomy.

Design outcomes

Primary

MeasureTime frame
five-year survival rate;—

Secondary

MeasureTime frame
Drug sensitivity rate;—

Countries

China

Contacts

Public ContactYao Yuanqing

The Seventh Medical Center of Chinese PLA General Hospital

yqyao_ghpla@163.com+86 188 1112 0675

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026