obesity
Conditions
Interventions
Hypercapnia group:Hypercapnia under lung-protective ventilation strategies
Normal capnia group:Normal capnia under lung-protective ventilation strategy
Sponsors
The First People's Hospital of Lianyungang City
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years old; 2. ASA Grading I-III; 3. The patient's BMI >= 40 kg/m2, BMI of 35-40 kg/m2 with related complications, BMI of 30-35 kg/m2 with type 2 diabetes and/or poorly controlled hypertension; 4. Patients who electively undergo laparoscopic sleeve gastrectomy in the reverse Trendelenburg position; 5. Have a clear understanding and voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Received other experimenters within 30 days before the study; 2. The patient has severe visual and hearing impairment, or is unable to communicate with the investigator for other reasons; 3. Presence of a history of heart failure pneumothorax, severe chronic obstructive pulmonary disease and emphysema; 4. Unilateral or bilateral rScO2 <= 55% preoperatively; 5. Other reasons that the investigator considers unsuitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the oxygen saturation curve of intraoperative brain tissue; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum S100ß protein;Postoperative pulmonary complications;Drive pressure; | — |
Countries
China
Contacts
Public ContactYing Chen
The First People's Hospital of Lianyungang City
Outcome results
None listed