POD
Conditions
Interventions
olfactory training:preoperative olfactory training
control:None
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Patients undergoing cardiac surgery under general anesthesia; 2)18 years old = age =85 years old, gender is not limited, ASA grade =III; 3) No recent history of surgery, operation time =2 hours. 4) Can communicate normally, be able to cooperate and complete cognitive function tests. MMSE score >17 points. 5) Several family members of the patient are aware and willing to cooperate and participate.
Exclusion criteria
Exclusion criteria: 1) Emergency surgery; 2) People with brain diseases or a history of brain diseases such as cerebral infarction, stroke, etc.; 3) A history of neurological and psychological disorders, including Alzheimer's disease, Parkinson's disease, psychosis, etc.; 4) Severe hearing or vision impairment; 5) Those who have taken psychotropic drugs or abused psychotropic drugs within 1 month; 6) Rhinitis, sinusitis, previous nasal surgery history, nasal congestion, upper respiratory tract infection in the past two weeks and other diseases that may affect olfactory function. 7) Patients allergic to pollen and olfactory agents. 8) Patients who cannot cooperate or refuse to sign informed consent 9) patients with Alzheimer's disease and Parkinson's disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of postoperative deliirum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of postoperative delirium;TDI score of olfactory function 7 days before and after surgery;Blood molecular biomarkers;Inflammatory indicators; | — |
Countries
China
Contacts
Public ContactYanni Fu
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed