Urolithiasis
Conditions
Interventions
DT Group:Potassium sodium hydrogen citrate granules were used for oral stone dissolution
Control Group:None
Sponsors
Changshu Hospital affiliated to Soochow University( Changshu No. 1 People's Hospital)
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: All stone patients were diagnosed using urologic ultrasonography, kidney-ureter-bladder (KUB) X-ray, or abdominal computed tomography (CT). Stone samples were obtained through ureteroscopic lithotripsy (URSL), percutaneous nephrolithotomy (PCNL), or extracorporeal shock wave lithotripsy (ESWL). Stones were analyzed using an automated infrared spectroscopy system, LIIR-20 (Lanmode Scientific Instrument Co., Ltd., Tianjin, China), and the main components were determined based on the most abundant substances listed in the report, which were classified as pure or mixed uric acid stones (anhydrous uric acid content >50%).
Exclusion criteria
Exclusion criteria: 1. Patients with malignancy, chronic liver insufficiency, a history of statin use, and thyroid or parathyroid disease were excluded from the study. 2. Participants were also excluded if they had taken antibiotics or immune suppressants within one month prior to fecal sampling, or had a history of chronic diarrhea or constipation, chronic enteritis, irritable bowel syndrome, gastrointestinal tumors or intestinal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota;Fecal short chain fatty acids contents;Maximum stone diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum triglyceride;Total serum cholesterol;Serum high density lipoprotein cholesterol;Serum low density lipoprotein cholesterol;Serum uric acid;Serum creatinine;Serum potassium;Serum calcium;Serum magnesium;Urine ph; | — |
Countries
China
Contacts
Public ContactCheng Cao
Changshu Hospital Affiliated to Soochow University (Changshu No.1 People's Hospital)
Outcome results
None listed