Lung Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 50 and 75 years old; 2. Received high school (including secondary specialized schools) education or above; 3. Patients who are aware of their diagnosis and planning to undergo lung resection surgery; 4. Body mass index within normal range: 18.5=BMI=23.9; 5. Mild to moderate decrease in baseline lung function before surgery: 50%= FEV1%<65%; 6. Health literacy score (BHLS) =10, able to independently use smart devices to complete electronic questionnaires; 7. Clear consciousness, no communication or cognitive impairment, signed informed consent form;
Exclusion criteria
Exclusion criteria: 1. Preoperative ECOG performance status =1; 2. Longest diameter of lung nodule on CT =8cm; 3. Patients who have received neoadjuvant therapy before surgery; 4. Patients with history of thoracic surgery; 5. Evidence of continuous systemic corticosteroid use within 1 month before surgery; 6. Any unresolved toxicity greater than CTCAE grade 1 from previous treatment; 7. Patients unable to exercise due to physical disabilities from previous diseases or injury; 8. History of major diseases, including other malignancies within 5 years, angina, myocardial infarction, or stroke within 6 months; 9. Current severe or uncontrolled systematic diseases; 10. Other situations judged by researchers as unsuitable for inclusion;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in actual FEV1 value before and after 4 weeks of prehabilitation exercise ?FEV1 (L); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in lung function before and after 4 weeks of prehabilitation exercise: including FVC , PEF, MVV, DLco, FEV1%;Change in actual FEV1 value at 1 month after surgery compared to baseline ?FEV1 (L);Incidence of postoperative pulmonary complications (PPCs) within 1 month after surgery;Pulse oximetry oxygen saturation (SaO2) on postoperative day 2; | — |
Countries
China
Contacts
West China Hospital of Sichuan University