Hepatectomy
Conditions
Interventions
Group C:Sham-Remote Ischemic Conditioning (at the time points of 30 min before anesthesia, 30 min after surgery, the morning of the postoperative day 1, the afternoon of the postoperative day 1, the m
Group 1:Remote Ischemic Conditioning (at the time points of 30 min before anesthesia, the morning of the postoperative day 1, the morning of the postoperative day 2): Three cycles (30 minutes), each c
Group 2:Remote Ischemic Conditioning (at the time points of 30 min before anesthesia, 30 min after surgery, the morning of the postoperative day 1, the afternoon of the postoperative day 1, the mornin
Sponsors
The Second Affiliated Hospital, Chongqing Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Patients undergoing hepatectomy under general anesthesia; ? ASA grade of II ~ III; ? Male and female patients, age 25 to 75 years; ? NYHA grade of I ~ III.
Exclusion criteria
Exclusion criteria: ? Patients with limb deformity or peripheral vascular disease affecting upper limb function; ? Patients with a medical history of nervous system, immune system and mental illness; ? Patients who have received hepatectomy in the past, have important organ diseases or have undergone surgical treatment recently; ? Patients who have recently used anti-inflammatory analgesics, anticoagulants, hormone drugs, immunosuppressants, and ATP-sensitive K-channel blockers (KATP); ? Preoperative severe renal insufficiency (serum creatinine > 442 umol/L, with or without serum potassium > 6.5 mmol/L, or the clinician-recognized need for renal replacement therapy), liver insufficiency (Child-Pugh grade C); ? Patients and/or their family members refuse to participate in the program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT; | — |
Secondary
| Measure | Time frame |
|---|---|
| AST;TBIL;INR;ALB;TNF-a;MDA;HO-1;NF-?B;HMGB1;Platelet;WBC;Neutrophil granulocyte percentage;Time to gastrointestinal tolerance;Prolonged postoperative ileus;Postoperative complications; | — |
Countries
China
Contacts
Public ContactHe Huang
The Second Affiliated Hospital, Chongqing Medical University
Outcome results
None listed