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The role of lower limb biomechanical markers measured by low-dose CT in the construction of a predictive model for the pathogenesis and regression of knee osteoarthritis

The role of lower limb biomechanical markers measured by low-dose CT in the construction of a predictive model for the pathogenesis and regression of knee osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077517
Enrollment
Unknown
Registered
2023-11-10
Start date
2022-08-24
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Non-exposed group:N/A

Sponsors

Peking University Shougang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: Permanent residence in the Beijing area. Han Chinese. 25 years of age or older. Diagnosis of osteoarthritis of the knee according to the American College of Rheumatology (ACR) 2016 edition criteria. A Kellgren-Lawrence (K-L) classification of Grade 1-3.

Exclusion criteria

Exclusion criteria: Combination of rheumatoid arthritis, ankylosing spondylitis, and other rheumatologic and immunologic diseases that may cause joint diseases of the lower extremities; Combination of limb tumors, developmental abnormalities, post-traumatic deformity healing, etc. that may cause lower limb force line abnormalities due to reasons other than osteoarthritis; Combination of cerebrovascular disease, peripheral neuropathy and other medical diseases that may affect the activity and normal function of the lower limbs; Those with a clear history of soft tissue injury within the knee joint; Deafness, mental illness, and other conditions that may affect normal communication ability.

Design outcomes

Primary

MeasureTime frame
Progression of osteoarthritis of the knee;

Secondary

MeasureTime frame
All-cause death;Patient underwent lower extremity orthopaedic surgery, total artificial knee replacement or unicompartmental artificial knee replacement;

Countries

China

Contacts

Public ContactGuan Zhenpeng

Peking University Shougang Hospital

guanzhenpeng@qq.com+86 186 1176 2066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026