Depression with non-suicidal self-injury
Conditions
Interventions
iTBS+MBSR:iTBS stimulation and Mindfulness-based stress reduction trainings
pcTBS+MBSR:pcTBS stimulation and Mindfulness-based stress reduction trainings
Sham+MBSR:Sham stimulation and Mindfulness-based stress reduction trainings
MBSR:Mindfulness-based stress reduction trainings
Sponsors
Hangzhou Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Aged 12 to 18 years old; (2) Meet the diagnostic criteria of the American Diagnostic and Statistical Manual of Mental Disorders (DSM-5) for depression; (3) There have been at least 5 NSSI behavior in the past 12 months (intentional damage to one's own body tissue without suicidal intention), at least 1 NSSI behavior in the past month; (4) Hamilton Depression Rating Scale 17 items (HAMD-17) = 17 points, Young's Mania Rating Scale = 5 points; (5) Primary school education or above and be able to understand the contents of the informed consent form; (6) Both patients and guardians give informed consent.
Exclusion criteria
Exclusion criteria: (1) Currently or in the past manic episodes, schizophrenia, and borderline personality disorder; (2) Current or past history of substance abuse or dependence, mental illness, or family history of self-injurious behavior; (3) Other systemic symptoms or patients with secondary depression caused by organic diseases or drugs; (4) currently or in the past combined with neurological diseases or other serious physical diseases; (5) currently having an appointment with a cognitive behavioral psychotherapist or psychotherapist; (6) Patients with contraindications to transcranial magnetic stimulation (history of epilepsy, severe head injury, implanted devices (such as pacemakers, medical pumps), metal on the head, pregnancy or lactation, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| self-injurious thoughts and behaviors;heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| impulsiveness;depression;anxiety;sleep quality ;brain activity; | — |
Countries
China
Contacts
Public ContactYonghui Shen
Hangzhou Seventh People's Hospital
Outcome results
None listed