talipes equinovarus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Prenatal ultrasound suggested that the fetus had CTEV;2.Fetuses with poor prognosis after birth or isolated talipes equinovarus diagnosed prenatally were corrected after birth.
Exclusion criteria
Exclusion criteria: 1. History of teratogenic drug use and infection during pregnancy; 2. Incomplete clinical data and fetal specimen sampling was not performed;3.loss to follow up;4.Abortion is performed or there is no adverse prognosis after birth or the phenotype of prenatal diagnosis is consistent with that of the postpartum period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pathogenic variant; | — |
Secondary
| Measure | Time frame |
|---|---|
| likely pathogenic variant; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Zhengzhou University