schizophrenia
Conditions
Interventions
1:iTBS+FBT
2:iTBS+HE
3:sham-iTBS+FBT
4:sham-iTBS+HE
Sponsors
Beijing Huilongguan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Comply with the Diagnostic Criteria for Mental Disorders Diagnostic Statistics Manual (DSM-IV) for schizophrenia; 2. PANSS positive amount form item score <5 points, positive scale total score <22 points; 3. Aged 18-65 Years, received more than 6 years of formal education; 4. patients volunteered to participate in the study, and signed informed consent; 5. the past four weeks and estimated the next eight weeks the drug types, doses do not need to be adjusted; 6. the existence of cognitive damage: the number down Back breadth = <6; 7. right hand, using the Edinburgh hand evaluation scale to determine.
Exclusion criteria
Exclusion criteria: 1, with mental retardation or brain organic disease; 2, severe decline or impulsive excitement; 3, accompanied by severe depression, anxiety and substance abuse; 4, metal foreign bodies in the body should not be MRI scan; 5, serious Physical illness or side effects of drugs, unable to carry out cognitive training; 6, pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Repeatable Battery for the Assessment of Neuropsychological Status,RBANS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and Negative Syndrome Scale,PANSS;Self-Rating Depression Scale,SDS;Self-Rating Anxiety Scale,SAS;SymptomChecklist-90,SCL-90;Short From Health Survey, SF-36;Self-esteem Scale,SES;Personal and Social Performance Scale,PSP;Temporal Experience of Pleasure Scale, TEPS;Morphological structure parameters of gray matter and white matter;Functional plasticity parameters;Treatment Emergent Symptom Scale;Gra Bar Test,GBT;Maze Pathfinding Test,MPT; | — |
Countries
China
Contacts
Public ContactJiaqi Song
Beijing Huilongguan Hospital
Outcome results
None listed