asthma
Conditions
Interventions
Control group:Healthy patients do not intervene
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Observation Group: (1) Right-handed; (2) Age 18-60 years old; (3) Consistent with the above asthma history or typical clinical symptoms; (4) Diagnosed with asthma according to the diagnostic criteria that meet the guidelines for the prevention and treatment of bronchial asthma (2022 edition), and the bronchodilator test is positive (after inhalation of bronchodilators, FEV1 increases by >12%, and the absolute value of FEV1 increases by >200 ml) (5) You can lie quietly for more than 30 minutes; (6) Agree to the rules of this study and sign a paper informed consent form. Inclusion Criteria for the Control Group: (1) Right-handed; (2) Age range 15-60 years old; (3) Male or female; (4) Have not received medication and related physical therapy or acupuncture therapy within 1 month in the past; (5) No contraindications to magnetic resonance examination, no systemic diseases; (6) Able to understand the process of conducting this study and agree to sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Observation Group: (1) Participated in other clinical trials within one month; (2) Received systemic glucocorticoid therapy within two weeks; (3) Systemic infection, respiratory tract infection, tuberculosis or fungal infection within 1 month; (4) Admitted to the hospital for acute asthma exacerbation within 2 months prior to enrollment; (5) Those who cannot stop the use of glucocorticoids, theophylline, long-acting ß receptor blockers, cromolyn sodium, leukotriene antagonists, anticholinergic drugs, or are sensitive to albuterol and glucocorticoids; (6) Concomitant other serious primary diseases (including hypertension, tumor, hyperthyroidism, bronchiectasis, cardiac insufficiency, etc.), or participation in this study may make the subject dangerous; (7) Female pregnancy or lactation; (8) There are contraindications to acupuncture, such as severe specific dermatitis or bleeding (such as thrombocytopenic purpura, hemophilia, etc.); (9) There are contraindications to magnetic resonance examination such as claustrophobia; (10) You can't lie down quietly. Control Group Exclusion Criteria: (1) Uncontrolled acute respiratory diseases in the past month, including but not limited to upper respiratory tract infection, pneumonia, bronchiectasis, etc.; (2) Previous obstructive sleep apnea syndrome (OSAS), etc.; (3) Combined with neuropsychiatric diseases, such as depression, schizophrenia, epilepsy, stroke, depression, etc.; (4) Special conditions in the body such as hearing aids and pacemakers that are not suitable for magnetic resonance examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function tests; | — |
Secondary
| Measure | Time frame |
|---|---|
| Asthma control test score;Pain level;Number of symptom-free days;Number of asthma exacerbations;rs-fMRI; | — |
Countries
china
Contacts
Public ContactWei Xiangyu
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed