knee osteoarthritis
Conditions
Interventions
Control group A was blank:Routine total knee arthroplasty and postoperative treatment
Experiment group B:Routine total knee replacement and postoperative treatment + aesculin sodium to reduce swelling
Experiment Group C:Routine total knee arthroplasty and postoperative treatment + aesculin sodium for swelling reduction + magnesium sulfate wet compress
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
30 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients with knee osteoarthritis had clear indications for surgery and underwent total knee replacement for the first time. The general basic condition is good; The ASA grade is ?-?. Patients who can cooperate with the completion of treatment and have no obvious neurological or psychiatric diseases.
Exclusion criteria
Exclusion criteria: Patients with knee joint infectious inflammation; Patients with rheumatoid arthritis; People who are allergic to nonsteroidal anti-inflammatory analgesics, glucocorticoids, opioids, and 50% magnesium sulfate solution; Patients with serious heart, lung and other vital organ diseases who cannot receive surgery; A history of hepatic and renal insufficiency; ASA anesthesia score > ? grade; Patients requiring hormone therapy due to autoimmune disease and those with a history of glucocorticoid use in the 3 months prior to surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog score of knee joint;Limb circumference measurement;Knee range of motion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee function HSS score;Invisible blood loss calculation;Inflammatory index; | — |
Countries
China
Contacts
Public ContactChen Lu
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed