sepsis
Conditions
Interventions
Gold Standard:qSOFA score
Index test:Cognitive AI and bile acid testing.
Sponsors
East Hospital Affiliated to Tongji University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18-80 years, both genders. 2. The diagnostic criteria for sepsis in Sepsis 3.0 are as follows: For patients with infection or suspected infection, when the qSOFA score (respiratory rate = 22 breaths/min, altered mental status, and systolic blood pressure = 100 mmHg, with 1 point assigned to each criterion) is = 2, further assessment should be conducted to determine if the patient has organ dysfunction. If the patient's SOFA score changes by = 2 points, it indicates the presence of organ dysfunction and the diagnosis of sepsis. The diagnostic criteria for septic shock are as follows: The patient has already been diagnosed with sepsis and presents with persistent hypotension despite adequate fluid resuscitation, requiring vasopressor therapy to maintain a mean arterial pressure = 65 mmHg (1 mmHg = 0.133 kPa), and a serum lactate level > 2 mmol/L. 3. The informed consent form should be signed.
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years. 2. Patients with mental illness. 3. Pregnant or lactating women. 4. Patients with anuria (lack of urine production). 5. Patients with incomplete clinical data in the electronic medical record system. 6. Patients diagnosed with HIV. 7. Patients who refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bile acid metabolism;Sensitivity;Specificity;Accuracy ; | — |
Secondary
| Measure | Time frame |
|---|---|
| arterial blood gas analysis;Analysis of acute infections;Emergency Biochemical analysis;procalcitonin;SOFA score;APACHE-? score;SIRS score;GCS score; | — |
Countries
China
Contacts
Public ContactLijun Liao
East Hospital Affiliated to Tongji University
Outcome results
None listed