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Difference in analgesic drug consumption and patients' comfort during colonoscopy under TCI propofol sedation: a comparative study of nalbuphine, oxycodone, and fentanyl

Difference in analgesic drug consumption and patients' comfort during colonoscopy under TCI propofol sedation: a comparative study of nalbuphine, oxycodone, and fentanyl - Consumption of different analgesics and comfort of patients under target-controlled sedation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077446
Enrollment
Unknown
Registered
2023-11-09
Start date
2023-11-09
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal pain during a painless colonoscopy

Interventions

Experiment group 1:Nalbuphine was given before examination
Experiment group 2:Oxycodone was given before examination
control group:Fentanyl was given before examination

Sponsors

Tianjin Jizhou District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria 1) Fibercolonoscopy was performed; 2) The patient voluntarily requested intravenous anesthesia; 3) Regardless of gender, age 18-65 years old; 4)ASA? or ? level; 5) Sign informed consent

Exclusion criteria

Exclusion criteria: Exclusion criteria 1) The patient has a history of neurological disease or mental illness and a history of drug allergy; 2) Surgical history within 1 month; 3) History of long-term use of analgesic drugs or other history of taking drugs that affect the test results; 4) A history of uncontrolled hypertension, arrhythmia, and heart failure; 5) History of obstructive sleep apnea (OSA), acute upper respiratory tract infection, asthma and other respiratory diseases; 6) According to the judgment of the investigator, patients who are not suitable for participation in this study for any reason other than the inclusion criteria and exclusion criteria.

Design outcomes

Primary

MeasureTime frame
Total use of analgesics (nalbuphine, oxycodone, fentanyl) /mg;

Secondary

MeasureTime frame
MAP;HR;SpO2;Breathing (whether mask pressure is required for oxygen/trachea intubation);body motion grade;Whether restless or not;

Countries

China

Contacts

Public ContactYan Li

Tianjin Jizhou District People's Hospital

drliyan@163.com+86 22 6011 1202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026