schizophrenia
Conditions
Interventions
stimulate group:The experimental group gave the second generation antipsychotic drugs based on sham stimulation twice a day of 2mA 20min starstimTDCS for transcranial direct current stimulation
sham group:False stimulation was given on the basis of the second-generation antipsychotics, and the stimulation intensity was consistent in site and stimulation time. At 2mA 20min twice daily for 5 c
Drug group:Second-generation antipsychotics
Sponsors
Third People's Hospital of Lanzhou City/ Gansu University Of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: The hospitalized patients from September 2023 to May 2024, who met the DSM-5 diagnostic criteria for schizophrenia, were hospitalized and receiving antipsychotic treatment for> 2 weeks, with PANSS score (60-120), (2) age 18-55 years old, male and female; (3) right-handed; (4) can cooperate with medical staff and sign informed consent. (5) cultural level of primary school or above. MoCA <26, (with MoCA (cognitive difficulties in screening subjects)
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) comorbidities meet ICD-10 other than schizophrenia, such as obsessive-compulsive disorder, phobia, anxiety disorder, depression, panic disorder or stress-related disorder; (2) clinical diagnosis of organic brain lesions: epilepsy, stroke, Alzheimer's disease, Parkinson's disease and other neurological diseases; medical (diabetes, hypothyroidism, myocardial infarction, etc.) with heart disease, pregnancy risk, cardiac pacemaker or any metal implant.(3) modified electroconvulsive therapy (modified electra convulsive therapy, MECT) within 1 month before evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA score;;B-CATSscore;SSPIscore; | — |
Secondary
| Measure | Time frame |
|---|---|
| PANSSscore; | — |
Countries
China
Contacts
Public ContactLi Yaju/ huo xiao ning
Gansu University Of Chinese Medicine/ Third People's Hospital of Lanzhou City
Outcome results
None listed