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Application of Bupivacaine Liposome Abdominal Transverse Muscle Planar Block Combined with Intravenous PCA for Postoperative Analgesia after Cesarean Section

Application of Bupivacaine Liposome Abdominal Transverse Muscle Planar Block Combined with Intravenous PCA for Postoperative Analgesia after Cesarean Section

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077433
Enrollment
Unknown
Registered
2023-11-08
Start date
2023-11-15
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after cesarean section

Interventions

group A:Ultrasound guided use of bupivacaine liposomes for horizontal abdominal muscle block combined with intravenous PCA
group B:Using intravenous patient-controlled analgesia
group C:Continuous epidural controlled analgesia

Sponsors

The First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age range from 19 to 45 years old, elective cesarean section, single term pregnancy, American Society of Anesthesiologists (ASA) grade I-II, less than 2 intraperitoneal surgeries, normal coagulation function.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Incomplete data, emergency cesarean section, preoperative complications of gastrointestinal diseases, such as chronic gastritis, colitis, intestinal tuberculosis, and irritable bowel syndrome; Concomitant with severe heart, brain, lung, liver, and kidney diseases; There are contraindications to spinal anesthesia, a history of chronic pain disorders, abdominal wall skin infection and damage, and a history of drug allergies used in the research institute.

Design outcomes

Primary

MeasureTime frame
72 hour postoperative analgesic effect score;Serum motilin levels, diamine oxidase, and D-lactate concentration levels;

Secondary

MeasureTime frame
Postoperative recovery time of bowel sounds;Effective number of compressions with self-control analgesic pump;Number of analgesic remedies;Incidence of adverse reactions (dizziness, nausea, vomiting);Postoperative recovery quality score;

Countries

China

Contacts

Public ContactZhuang Guangying

The First Affiliated Hospital of Guangxi Medical University

86799488@qq.com+86 150 7717 6909

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026