Malnutrition
Conditions
Interventions
Experimental group:Cyproheptadine 0.1-0.2mg/kg, q12h+ Pancreatin
Control group:12-24M: pancreatin 75mg bid
24-36M: pancreatin: 150mg bid
Sponsors
Guangdong Provincial People's,Guangdong Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 3 Years
Inclusion criteria
Inclusion criteria: Simultaneously meet the following three requirements: a) Male or female, aged 1-3 years; b) Meets the above diagnostic criteria for malnutrition; c) Stable vital signs; d) The parents or guardians of the child understand the research purpose and sign a written letter of understanding.
Exclusion criteria
Exclusion criteria: Meet any one of the following conditions: a) Allergy to cyproheptadine; b) According to the clinical judgment of the investigator, the current or previous diseases/conditions that may interfere with this study or its outcome parameters are known, such as liver and kidney dysfunction, gastrointestinal malformations, congenital, genetic or metabolic diseases, autoimmune diseases or immune deficiency diseases, active tuberculosis, inflammatory bowel disease, chronic lung diseases, malignant tumors or children undergoing major surgery; c) Those who have participated in other projects or are deemed unsuitable for inclusion by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight;Height;Fecal microbiota;Food allergy source;Urinary amino acid metabolism;Blood organic acid metabolism;Blood fatty acid metabolism;Clinical symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;Alanine aminotrans feras;Albumin; | — |
Countries
China
Contacts
Public ContactMin-Yang
Guangdong Provincial People's,Guangdong Academy of Medical Sciences
Outcome results
None listed