stroke
Conditions
Interventions
Control group:sham stimulation
Sponsors
Wuxi Mental Health Center
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?individuals who had experienced their first unilateral stroke; ?hemiparesis due to left or right subcortical lesion confirmed by brain computed tomography (CT) or MRI; ?age between 40 and 80, male or female; ?stable condition with a duration of 3-12 months since stroke onset; ?ability to independently walk over 10 meters with or without orthosis; ?Brunnstrom lower limb stages III-V; ?capable of communicating in a simple manner sufficient for trial intervention and assessment completion; ?informed consent signed by the patients.
Exclusion criteria
Exclusion criteria: ?standard contraindications to iTBS or fMRI, such as the presence of irremovable metal objects in and around the body (e.g., cardiac pacemaker, implanted medication pump); ?obvious impairments in speech, attention, hearing, vision, intellect, mental state or cognition (MMSE4); ?presence of other severe medical conditions that can affect outcome assessment results including cardiovascular disease, endocrine disorders, hepatic dysfunction and renal diseases; ?currently enrolled in other clinical trials; ?poor compliance with treatment regimens; ?other situations deemed unsuitable for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ten-meter walking test,10 MWT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-meyer Assessment Lower Extremity, FMA-LE;time ''up and go'' test, TUGT;modified Barthel index, MBI; functional ambulation category scale,FAC;Berg balance scale, BBS;Evaluation of Static and Dynamic Stability;3D gait analysis;Surface electromyography;Corticomotor excitability;MMSE;MoCA;fMRI; | — |
Countries
China
Contacts
Public ContactQian yao
Wuxi Mental Health Center/Wuxi Central Rehabilitation Hospital
Outcome results
None listed