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Nasopharyngeal stimulation for Prevention of Respiratory Depression in Patients under Propofol Sedation during Gastroscopy:a randomized controlled trial

Nasopharyngeal stimulation for Prevention of Respiratory Depression in Patients under Propofol Sedation during Gastroscopy:a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077383
Enrollment
Unknown
Registered
2023-11-07
Start date
2023-11-10
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia

Interventions

Prevention Group:When the Ramsay sedation rating of the patient is greater than 4, hold the tail of the swab with one hand and stick it to one side of the nostril to enter. Slowly penetrate 1-1.5 cent
Control Group:None

Sponsors

The Third Affiliated Hospital of Sun Yat sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) The patient and their legal representative voluntarily participate in the study and sign an informed consent form; (2) Patients who only undergo gastroscopy examination at this center. (3) American Society of Anesthesiologists (ASA) grading I - II; Age = 18 years old and = 65 years old.

Exclusion criteria

Exclusion criteria: (1) The patient has a history of nasal deformities, nasal mucosal damage and bleeding, and moderate to major nasal surgeries. (2) Patients undergoing gastroscopy treatment at this center. (3) Concomitant severe respiratory diseases. (4) Full stomach or clear risk of reflux aspiration. (5) The baseline blood oxygen saturation of the patient is less than 95%. (6) Combined with other important organ dysfunction: including severe liver and kidney dysfunction; Organic brain diseases, specifically referring to aneurysmal vascular diseases or arteriovenous malformations and cerebral hemorrhage; Severe hypertension, coronary heart disease, cardiac dysfunction (NYHA = Grade III), pulmonary hypertension; Hematological system diseases; Abnormal coagulation function.

Design outcomes

Primary

MeasureTime frame
The incidence of hypoxemia;

Secondary

MeasureTime frame
Related indicators of sneeze reflex induction;Incidence of subclinical hypoxia;Vital signs of patients during surgery;

Countries

China

Contacts

Public ContactZiqing Hei

The Third Affiliated Hospital of Sun Yat sen University

heizq@mail.sysu.edu.cn+86 189 2210 2601

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026