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Protective mechanism of mannitol on donor lung in lung transplantation

Protective mechanism of mannitol on donor lung in lung transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077351
Enrollment
Unknown
Registered
2023-11-06
Start date
2023-11-12
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage lung disease

Interventions

20% mannitol 1ml/kg group (M1):1ml/kg mannitol igtt
20% mannitol 3ml/kg group (M2):3ml/kg mannitol igtt
20% mannitol 5ml/kg group (M3):5ml/kg mannitol igtt
0.9%NaCl control group(C group):0.9%NaCl igtt

Sponsors

The Affiliated Wuxi people's Hospital of Nanjing Medical University, Wuxi Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: patients undergoing lung transplantation, ASA II-III

Exclusion criteria

Exclusion criteria: The patient's cardiac function was NYHA class III and with renal insufficiency to anuria

Design outcomes

Primary

MeasureTime frame
Inflammation and oxidative stress;—

Secondary

MeasureTime frame
Hemodynamic parameters;arterial blood gas analysis;—

Countries

China

Contacts

Public ContactXu Bo

The Affiliated Wuxi people's Hospital of Nanjing Medical University, Wuxi Medical Center

xubo1028@sina.com+86 180 6825 1681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026