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Biomarkers of cardiac microvascular endothelial injury in diabetes mellitus

Biomarkers of cardiac microvascular endothelial injury in diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300077350
Enrollment
Unknown
Registered
2023-11-06
Start date
2023-11-12
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes

Interventions

Patients with diabetes and coronary heart disease:NA
Non diabetes patients with coronary heart disease:NA

Sponsors

Xijing Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age of 18-80 years old; (2) within 3 days of onset; (3) patients with a definite diagnosis of coronary heart disease and undergoing angiography; Case group: (1) Age 18-80 years old; (2) Within 3 days of onset; (3) Patients diagnosed with coronary heart disease and undergoing angiography; (4) Fasting blood glucose exceeds 7.0mmol/L, or random blood glucose exceeds 11.1mmol/L;

Exclusion criteria

Exclusion criteria: (1) those without informed consent; (2) allergic diseases such as asthma and chronic obstructive pulmonary disease; (3) High fever, pregnancy, severe infection, malignant tumor, severe liver and kidney dysfunction; (4) rheumatic immune-related diseases; Blood system diseases; Skeletal muscle injury; Nervous system diseases; (5) patients who did not receive treatment or withdrew from the study during treatment;

Design outcomes

Primary

MeasureTime frame
Indexofmicro -circulationresistance;

Secondary

MeasureTime frame
Serum protein level indicators: Rbm3, S100a6, Fstl1, Mgp, Ctsh;

Countries

China

Contacts

Public ContactDongdong Sun

Xijing Hospital of Air Force Medical University

1048966441@qq.com+86 188 2939 5402

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026