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Clinical trial of oral probiotics in the adjuvant treatment of vaginitis in pregnant women

Clinical trial of oral probiotics in the adjuvant treatment of vaginitis in pregnant women

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077342
Enrollment
Unknown
Registered
2023-11-06
Start date
2022-04-10
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginitis during pregnancy

Interventions

Experimental group:Conventional management+Adjuvant therapy with probiotics

Sponsors

Jinan Maternity and Child Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Meet the clinical diagnostic criteria of vaginitis. 2. The age of pregnant women was 22-45 years old, and the gestational age was 12-37 weeks. 3. No medication was used within 2 weeks before the visit. 4. Patients who agree to receive this treatment and can be followed for observation. 5. Did not receive steroids and broad-spectrum antibiotics in the past 2 months. 6. Singleton pregnancy.

Exclusion criteria

Exclusion criteria: 1. Hanging drop method (-), pseudohyphal yeast culture (-). 2. Severe hepatic and renal insufficiency. 3. Allergic history to clotrimazole suppository and metronidazole drugs, and topical use in the past 2 weeks. 4. Inability to participate or provide follow-up data for at least 2 months. 5. Patients with autoimmune diseases or low immunity. 6. People with AIDS. 7. Patients with lupus erythematosus. 9. Patients with asthma. 10. Other chronic or acute diseases that may affect the results.

Design outcomes

Primary

MeasureTime frame
Evaluation of vaginal microecology;

Secondary

MeasureTime frame
Clinical signs and symptoms;

Countries

China

Contacts

Public ContactCuiying Liu

Jinan Maternity and Child Care Hospital

joyliu007@163.com+86 180 5315 3120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026