therapeutic effect of traditional Chinese medicine comprehensive therapy on lower limb nerves and blood flow in patients with acute ischemic stroke combined with hypertension

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300077336

Enrollment

Unknown

Registered

2023-11-06

Start date

2023-11-06

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Conventional treatment group:Routine medical drug treatment, including intravenous thrombolysis (alteplase 0.9mg/kg intravenously pumped), double antibody (aspirin enteric coated tablets 100mg once da

Tianma Gouteng Decoction modified group:Routine treatment combined with Tianma Gouteng Decoction

Electroacupuncture group:Conventional treatment combined with electroacupuncture stimulation of relevant acupoints

Comprehensive treatment group:Comprehensive treatment of Tianma Gouteng Decoction plus or minus external electroacupuncture on the basis of conventional treatment

Eligibility

Sex/Gender

All

Age

45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) It meets the diagnostic criteria of ischemic stroke in the Chinese guidelines for the diagnosis and treatment of acute ischemic stroke 2018 issued by the Chinese Medical Association; 2) It met the diagnostic criteria for hypertension in the 2010 Revision of the guidelines for the prevention and treatment of hypertension in China; 3) Age = 75 years old, onset time = 7 days; 4) TCM syndrome differentiation is hyperactivity of liver yang; 5) Be able to cooperate with rehabilitation scale assessment and lower extremity vascular examination; 6) Voluntarily participate in the clinical trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Identify lower limb dysfunction not caused by stroke; 2) Patients with severe primary chronic diseases such as heart, liver, kidney, hematopoietic system and endocrine system; 3) Patients with lower limb ulcers and skin ulcers; 4) Patients who could not complete brain MRI+DWI; 5) Metal parts or implanted electronic devices (such as cardiac pacemakers) in the body; 6) Severe bleeding tendency.

Design outcomes

Primary

Measure	Time frame
Lower limb motor function;Lower limb sensory function;Lower limb balance function;Lower extremity arterial blood flow;	—

Secondary

Measure	Time frame
Adverse reactions;	—

Countries

China

Contacts

Public ContactYAN JUN

Xi'an Fifth Hospital

263329976@qq.com+86 135 7203 4347

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026