Glucocorticoid osteoporosis
Conditions
Interventions
treatment group:Oral 600mg calcium carbonate D3 once daily
Oral 0.5ug alfacalcitol tablets once daily
Oral Goldtiger capsules, three capsules three times a day
control group:Oral 600mg calcium carbonate D3 once daily
Oral 0.5ug alfacalcitol tablets once daily
Ritidronate sodium 35mg was given orally once a week
Sponsors
Henan Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (i) patients with glucocorticoid-treated related diseases who have been treated with glucocorticoid for more than 3 months; (ii) patients who meet the diagnostic criteria for osteoporosis; (iii) people with good compliance; and (iv) those who voluntarily signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) patients with primary osteoporosis or secondary osteoporosis caused by non-glucocorticoid hormones; (2) patients with cardiac, hepatic, renal, pulmonary and other vital organ insufficiency; (3) patients with hormone-related diseases, such as pituitary, thyroid, parathyroid, adrenocortical dysfunction of the disease (hyper- or hypocorticism) and other histories; (4) patients who have taken drugs affecting bone metabolism within six months; (5) patients with bone loss due to other causes (such as tumors, osteochondritis dissecans, hyperparathyroidism, Paget's disease, osteogenesis imperfecta, and other diseases); (6) patients with a history of mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bone densitometry;Markers related to bone metabolism; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skeletal muscle evaluation indicators;VAS score;Quantitative grading score of TCM syndromes;Quality of Life Measures; | — |
Countries
China
Contacts
Public ContactDongliang Shi
Henan Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed