Early stage triple negative breast cancer
Conditions
Interventions
Triple-negative Breast Cancer Patients:NA
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Female Chinese patient =18 years old at time of early stage TNBC diagnosis; 2) Patient must have a histologically documented diagnosis of either T1c N1-2 or T2-4 N0-2*(stage IIA~IIIB) TNBC (histologically documented ER-, PR- and HER2-); 3) Patient has a biopsy or surgical resection sample from a newly obtained or an archival tissue block of maximum three years old available for PD-L1 testing?; 4) No prior systemic therapy including but not limited to chemotherapy, immunotherapy, target therapy for early TNBC before sample material collection; 5) Patients must have informed consent form (ICF) signed for any future study or have conditions that are accepted by IRB/ERC to waive ICF or are willing to sign the informed consent form. * per AJCC for breast cancer staging criteria version 8 ? Newly-obtained specimen(collected up to 90 days prior to start of PD-L1 IHC test) is preferred to archived one
Exclusion criteria
Exclusion criteria: 1) Patient has only a specimen obtained with fine needle aspirate (FNA) or cytologic specimen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PD-L1 protein expression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Association between PD-L1 expression and demographic and clinicopathological features; | — |
Countries
China
Contacts
Public ContactBu Hong
West China Hospital of Sichuan University
Outcome results
None listed