Intrauterine diseases
Conditions
Interventions
Esketamine group:Esketamine
Sponsors
The First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-65 years old; (2) Preoperative blood routine, biochemical, and electrocardiogram examinations have been completed without obvious abnormalities; (3) The American Anesthesiologists Association (ASA) is classified as Class I or II; (4) No respiratory, circulatory, liver and kidney dysfunction, or endocrine disorders; (5) Mallampati improvement score = 3; (6) Body Mass Index (BMI) 18-28 kg/m2.
Exclusion criteria
Exclusion criteria: (1) Individuals who are allergic to drugs such as esketamine, opioids, and propofol; (2) Severe dysfunction of organs such as the heart, lungs, liver, and kidneys; (3) Have a history of upper respiratory tract infection in the past 2 weeks; (4) Poor control of hypertension; (5) Hyperthyroidism; (6) Suffering from neurological and psychiatric disorders such as epilepsy and cognitive dysfunction; (7) Have taken benzodiazepines or opioids within the past 3 months; (8) Participated in clinical trials of other drugs within the past 3 months; (9) The patient and their family members refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Respiratory deppression;Incidence of adverse events (circulatory system); | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction time;Recovery time;Other adverse events; | — |
Countries
China
Contacts
Public ContactZhang Kai
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed