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Impact of high-volume pericapsular nerve group (PENG) block on postoperative analgesia and motor function recovery following total hip arthroplasty: a prospective, observer-blinded randomized controlled trial

Impact of high-volume pericapsular nerve group (PENG) block on postoperative analgesia and motor function recovery following total hip arthroplasty: a prospective, observer-blinded randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300077281
Enrollment
Unknown
Registered
2023-11-03
Start date
2024-08-29
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip joint disease

Interventions

High-volume group:40 ml of 0.375% ropivacaine and 5mg of dexamethasone is administered when pericapsular nerve group (PENG) block is performed.
Regular-volume group:20 ml of 0.375% ropivacaine and 5mg of dexamethasone is administered when pericapsular nerve group (PENG) block is performed.

Sponsors

The Third Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. ASA physical status 1-3; 3. Weight 45-90 kg; 4. Primary unilateral total hip arthroplasty through posterolateral approach; 5. Coagulation function normal, no contraindication of regional anesthesia and spinal anesthesia; 6. Ability to report symptoms to researchers reliably.

Exclusion criteria

Exclusion criteria: 1. The patient refused; 2. Had a history of allergic reaction to local anesthetics; 3. Had infection near the puncture point; 4. Dementia or cognitive impairment; 5. Moderate or above anemia; 6. Pregnancy; 7. Chronic pain, and long-term intake of opioid analgesics.

Design outcomes

Primary

MeasureTime frame
Dynamic VAS pain score at 6 hours postoperatively;

Secondary

MeasureTime frame
Dynamic VAS pain score at 24, 48 hours postoperatively;The rest pain scores at 6 hours, 24 hours and 48 hours postoperatively;Postoperative sensory block of lower limbs;Motor function of lower limbs on postoperative side;Postoperative opioid breakthrough consumption;

Countries

China

Contacts

Public ContactZhaohui Chen, Qiansong Wang

The Third Affiliated Hospital of Chongqing Medical University

650688@cqmu.edu.cn+86 173 8239 5835

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 19, 2026